Bioinformatic Analysis of Alzheimer�s Disease and Type2 Diabetes Mellitus: A Bioinformatic Approach
نویسندگان
چکیده
منابع مشابه
Bioinformatic Analysis of Alzheimer’s Disease and Type2 Diabetes Mellitus: A Bioinformatic Approach
We evaluated the role of several proteins that are likely to be involved in alzheimers disease (AD) and type 2 diabetes mellitus (T2DM). By employing multiple sequence alignment using Clustalw tool, we have constructed a phylogenetic tree based on the functional protein sequences extracted form NCBI. The phylogram was constructed using neighbor joining algorithm. Our bioinformatic analysis repo...
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Growing evidence indicates that microRNAs (miRNAs) have a key role in processes involved in type 1 diabetes mellitus (T1DM) pathogenesis, including immune system functions and beta-cell metabolism and death. Although dysregulated miRNA profiles have been identified in T1DM patients, results are inconclusive; with only few miRNAs being consistently dysregulated among studies. Thus, we performed ...
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ژورنال
عنوان ژورنال: Journal of Proteomics & Bioinformatics
سال: 2008
ISSN: 0974-276X
DOI: 10.4172/jpb.s1000009